Anti-Calcium Pump PMCA3 ATPase antibody (ab154213)

Overview

  • Product name
    Anti-Calcium Pump PMCA3 ATPase antibody
    See all Calcium Pump PMCA3 ATPase primary antibodies
  • Description
    Rabbit polyclonal to Calcium Pump PMCA3 ATPase
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within internal sequence amino acids 560-887 of Human Calcium Pump PMCA3 ATPase (Uniprot ID: Q16720).

  • Positive control
    • U-87 MG whole cell lysate; Human U87 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab154213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 134 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Relevance
    Calcium Pump PMCA3 ATPase belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. Calcium Pump PMCA3 ATPase is the plasma membrane calcium ATPase isoform 3.
  • Cellular localization
    Cell membrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • ATP2B3 antibody
    • ATP2B3 protein antibody
    • ATPase Ca++ transporting plasma membrane 3 antibody
    • ATPase plasma membrane Ca2+ transporting 3 antibody
    • Plasma membrane calcium ATPase 3 antibody
    • Plasma membrane calcium ATPase isoform 3 antibody
    • Plasma membrane calcium pump isoform 3 antibody
    • Plasma membrane calcium transporting ATPase 3 antibody
    • PMCA 3 antibody
    • PMCA3 antibody
    • PMCA3a antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human U87 xenograft tissue, labeling Calcium Pump PMCA3 ATPase with ab154213 at 1/500 dilution.
  • Anti-Calcium Pump PMCA3 ATPase antibody (ab154213) at 1/1000 dilution + U-87 MG whole cell lysate at 30 µg

    Predicted band size: 134 kDa



    5% SDS PAGE

References

ab154213 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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