Overview

  • Product name
  • Description
    Rabbit polyclonal to CALHM1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Cow, Cat, Dog, Human, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 295-344 (GITDQGTMNR LLTSWHKCKP PLRLGQEAPL MSNGWAGGEP RPPRKEVATY) of Mouse CALHM1 (NP_001074740).

  • Positive control
    • Mouse Intestine lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
  • Tissue specificity
    Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells.
  • Sequence similarities
    Belongs to the FAM26 family.
  • Cellular localization
    Cell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAHM1_HUMAN antibody
    • Calcium homeostasis modulator 1 antibody
    • Calcium homeostasis modulator protein 1 antibody
    • CALHM1 antibody
    • FAM26C antibody
    • Family with sequence similarity 26, member C antibody
    • MGC39514 antibody
    • MGC39617 antibody
    • OTTHUMP00000020413 antibody
    • Protein FAM26C antibody
    see all

Images

  • Anti-CALHM1 antibody (ab116101) at 1 µg/ml + Mouse intestine lysate at 10 µg

    Predicted band size : 39 kDa

References

ab116101 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab116101.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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