Overview

  • Product nameAnti-CALHM1 antibody
    See all CALHM1 primary antibodies
  • Description
    Rabbit polyclonal to CALHM1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from Human CALHM1

Properties

Applications

Our Abpromise guarantee covers the use of ab87727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 38 kDa.

Target

  • FunctionMay be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
  • Tissue specificityPredominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells.
  • Sequence similaritiesBelongs to the FAM26 family.
  • Cellular localizationCell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAHM1_HUMAN antibody
    • Calcium homeostasis modulator 1 antibody
    • Calcium homeostasis modulator protein 1 antibody
    • CALHM1 antibody
    • FAM26C antibody
    • Family with sequence similarity 26, member C antibody
    • MGC39514 antibody
    • MGC39617 antibody
    • OTTHUMP00000020413 antibody
    • Protein FAM26C antibody
    see all

References for Anti-CALHM1 antibody (ab87727)

ab87727 has not yet been referenced specifically in any publications.

Product Wall



I agree that based on the homology between mouse and human CALHM1 (92% identical) I would expect a high alignment score between the immunogen and the mouse protein. I will continue to seek more information about the immunogen and will let you...

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Thank you for your call earlier this week.

I had contacted the lab to enquire about possible reactivity with mouse, and the BLAST results show a 7 amino acid overlap between the immunogen and the mouse putative sequence from SwissProt-
<...

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Thanks for your call today. I will be in touch with the production lab and will ask for more information about the immunogen used to make ab87727 or about the potential cross-reactivity with mouse. Please see below for information about your testing di...

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