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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Overview
Product name
Anti-Calpain 14 antibody - Carboxyterminal end, large subunit
See all Calpain 14 products (2) ...
Description
Rabbit polyclonal to Calpain 14 - Carboxyterminal end, large subunit
Specificity
ab28236 binds to calpain-14, but does not cross react with the other calpain family members (calpain-1, Calpain-2, ncl-2, ncl-3, etc.).
Tested applications
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide based on the carboxyterminal end of the large subunit of Human Calpain 14. (Peptide available as ab41372.)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Cysteine protease >> Calpains
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab28236 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: 1/1000 when using colorimetric substrates - 1/5000 for chemiluminescent substrates. Predicted molecular weight: 76 kDa and a series of further cleaved forms. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Calcium-regulated non-lysosomal thiol-protease.
Tissue specificity
Not expressed in tissues tested.
Sequence similarities
Belongs to the peptidase C2 family.
Contains 1 calpain catalytic domain.
Contains 3 EF-hand domains.
Target information above from: UniProt accessionA8MX76
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Calcium-activated neutral proteinase 14 antibody
- Calpain-14 antibody
- CAN14_HUMAN antibody
see all
Database links
- Entrez Gene: 440854 Human
- Omim: 610229 Human
- SwissProt: A8MX76 Human
- Unigene: 468059 Human
Protocols
References for Anti-Calpain 14 antibody - Carboxyterminal end, large subunit (ab28236)
ab28236 has not yet been referenced specifically in any publications.
Publishing research using ab28236? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"