Anti-Calpain 2 antibody [EPR2562Y] (ab75994)

Overview

• Product name
  Anti-Calpain 2 antibody [EPR2562Y]
  See all Calpain 2 primary antibodies
• Description
  Rabbit monoclonal [EPR2562Y] to Calpain 2
• Tested applications
  Suitable for: WB, IP, Flow Cytmore details
  Unsuitable for: ICC or IHC-P
• Species reactivity
  Reacts with: Human
  
• Immunogen

  A synthetic peptide corresponding to residues within human Calpain 2.

• Positive control
  • HeLa cytoplasmic or membrane lysate Permeabilized HeLa cells
• General notes

  This product is a recombinant rabbit monoclonal antibody.

  Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

  Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab^® patents

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• Storage buffer
  PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purity
  Tissue culture supernatant
• Clonality
  Monoclonal
• Clone number
  EPR2562Y
• Isotype
  IgG
• Research areas
  • Signal Transduction
  • Signaling Pathway
  • Calcium Signaling
  • Calpain

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes
  • Cysteine protease
  • Calpains

  • Cancer
  • Cancer Metabolism
  • Response to hypoxia

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Hypoxia

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Positive Controls
  • HeLa membrane extract lysate (ab29547)

Applications

Target

• Function
  Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
• Tissue specificity
  Ubiquitous.
• Sequence similarities
  Belongs to the peptidase C2 family.
  Contains 1 calpain catalytic domain.
  Contains 3 EF-hand domains.
• Cellular localization
  Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.

• Target information above from: UniProt accession P17655 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 824 Human
  • Omim: 114230 Human
  • SwissProt: P17655 Human
  • Unigene: 350899 Human
• Alternative names
  • Calcium activated neutral proteinase 2 antibody
  • Calcium activated neutral proteinase antibody
  • Calcium-activated neutral protease 2, catalytic subunit antibody

  • Calcium-activated neutral proteinase 2 antibody
  • CALP80 antibody
  • Calpain 2 (m/II) large subunit antibody
  • Calpain 2 catalytic subunit antibody
  • Calpain 2 large catalytic subunit antibody
  • Calpain 2 large subunit antibody
  • Calpain 2, large [catalytic] subunit antibody
  • Calpain large polypeptide L2 antibody
  • Calpain M type antibody
  • Calpain M-type antibody
  • Calpain-2 catalytic subunit antibody
  • Calpain-2 large subunit antibody
  • Calpain2 antibody
  • CAN2_HUMAN antibody
  • CANP 2 antibody
  • CANP L2 antibody
  • CANP2 antibody
  • CANPL 2 antibody
  • CANPL2 antibody
  • CANPml antibody
  • Capa2 antibody
  • CAPN 2 antibody
  • CAPN2 antibody
  • FLJ39928 antibody
  • M calpain antibody
  • M calpin antibody
  • M type antibody
  • M-calpain antibody
  • mCANP antibody
  • Millimolar calpain antibody
  • Millimolar-calpain antibody

  see all

Protocols

• Western blot protocols
• Flow cytometry protocols
• Immunoprecipitation protocols