Anti-Calpain S1 antibody [28F3] (Biotin) (ab78565)


  • Product nameAnti-Calpain S1 antibody [28F3] (Biotin)
    See all Calpain S1 primary antibodies
  • Description
    Mouse monoclonal [28F3] to Calpain S1 (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Cow, Human
    Does not react with: Mouse, Rat
  • Immunogen

    Human calpain from placenta

  • Positive control
    • Normal human fibroblast; A431 and Madin-Darby bovine kidney cells (MDBK) lysates.
  • General notesThis product was used in Hornberger W et al.,(2012) Novel approaches in label-free kinetic detection of small molecule ligand binding to receptor proteins using SAW (surface acoustic wave) technology. Poster Presented at Miptec Congress 2012



Our Abpromise guarantee covers the use of ab78565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa).
IP Use at an assay dependent dilution.


  • FunctionRegulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • Sequence similaritiesContains 5 EF-hand domains.
  • DomainThe contact of the 5th EF-hand domain from each monomer allows the formation of the homodimer and also appears to mediate the contact between the large catalytic subunit and small regulatory subunit for the formation of the heterodimer.
    EF-hand domains are paired. EF-hand 1 is paired with EF-hand 2 and EF-hand 3 is paired with EF-hand 4. The fifth EF-hand domain, left unpaired, does not bind the calcium but is responsible of the dimerization by EF-embrace. The first four EF-hand domains bind calcium, however it is not sure if the binding of EF-hand 4 to calcium is physiologically relevant.
  • Cellular localizationCytoplasm. Cell membrane. Translocates to the plasma membrane upon calcium binding.
  • Information by UniProt
  • Database links
  • Alternative names
    • 30K antibody
    • Calcium activated neutral proteinase antibody
    • Calcium activated neutral proteinase small subunit antibody
    • Calcium dependent protease small subunit 1 antibody
    • Calcium dependent protease small subunit antibody
    • Calcium-activated neutral proteinase small subunit antibody
    • Calcium-dependent protease small subunit 1 antibody
    • Calcium-dependent protease small subunit antibody
    • Calpain 4 antibody
    • Calpain 4 small subunit (30K) antibody
    • Calpain 4 small subunit antibody
    • Calpain regulatory subunit antibody
    • Calpain small polypeptide antibody
    • Calpain small subunit 1 antibody
    • Calpain4 antibody
    • CalpainS1 antibody
    • CANP antibody
    • CANP small subunit antibody
    • CANPS antibody
    • CAPN 4 antibody
    • CAPN S1 antibody
    • CAPN4 antibody
    • CAPNS 1 antibody
    • CAPNS antibody
    • Capns1 antibody
    • CDPS antibody
    • CPNS1_HUMAN antibody
    • CSS 1 antibody
    • CSS1 antibody
    see all

References for Anti-Calpain S1 antibody [28F3] (Biotin) (ab78565)

ab78565 has not yet been referenced specifically in any publications.

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