General notesab94278 is a 293T cell transfected lysate in which Human Calpastatin has been transiently over-expressed using a pCMV-Calpastatin plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
Similarity: Belongs to the protease inhibitor I27 (calpastatin) family.
Domain: Has four inhibitory domains.
PTM: The N-terminus is blocked.