Overview

  • Product name
    Calpeptin
  • Description
    Potent, cell-permeable calpain inhibitor
  • Biological description
    Potent, cell-permeable calpain inhibitor, a Ca2+-dependent protease. Ki values are 34 and 52 nM for μ- and m-calpains, respectively. Demonstrates neuroprotective effects suggesting ability to cross the blood-brain barrier.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Smith AW  et al. Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis. Invest Ophthalmol Vis Sci 52:4935-41 (2011). Read more (PubMed: 21613375) »
  • Rodríguez-Agudo D  et al. Rat histidine decarboxylase is a substrate for m-calpain in vitro. Biochem Biophys Res Commun 271:777-81 (2000). Read more (PubMed: 10814538) »
  • Tsujinaka T  et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin). Biochem Biophys Res Commun 153:1201-8 (1988). Read more (PubMed: 2839170) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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