Anti-Calponin antibody [CALP], prediluted (ab1408)

Overview

  • Product nameAnti-Calponin antibody [CALP], prediluted
    See all Calponin primary antibodies
  • Description
    Mouse monoclonal [CALP] to Calponin, prediluted
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Crude human uterus extract

  • Positive control
    • Myoepithelium in normal breast glands

Properties

Applications

Our Abpromise guarantee covers the use of ab1408 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notesIHC:
    This antibody is pre-diluted ready for use with an ABC system.
    For formalin fixed paraffin embedded sections, perform heat mediated antigen retrieval before commencing with IHC.
    Calponin has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast.
    Calponin has also been useful in malignant myoepithelium and pleomorphoric adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions.
  • Target

    • FunctionThin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
    • Tissue specificitySmooth muscle, and tissues containing significant amounts of smooth muscle.
    • Sequence similaritiesBelongs to the calponin family.
      Contains 3 calponin-like repeats.
      Contains 1 CH (calponin-homology) domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • Basic calponin antibody
      • Calponin 1 antibody
      • Calponin 1 basic smooth muscle antibody
      • Calponin H1 antibody
      • Calponin H1 smooth muscle antibody
      • Calponin-1 antibody
      • Calponin1 antibody
      • Calponins basic antibody
      • CNN 1 antibody
      • Cnn1 antibody
      • CNN1_HUMAN antibody
      • Epididymis secretory protein Li 14 antibody
      • HEL S 14 antibody
      • Sm Calp antibody
      • SMCC antibody
      • smooth muscle antibody
      see all

    References for Anti-Calponin antibody [CALP], prediluted (ab1408)

    ab1408 has not yet been referenced specifically in any publications.

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