Anti-Calsequestrin 1 antibody (ab126241)

Overview

  • Product name
    Anti-Calsequestrin 1 antibody
    See all Calsequestrin 1 primary antibodies
  • Description
    Rabbit polyclonal to Calsequestrin 1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 136-341 of Human Calsequestrin 1 (P31415).

  • Positive control
    • A549, HeLa, HepG2, HCT116 and Mouse heart whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78% PBS, 20% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126241 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 44 kDa.

Target

  • Function
    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.
  • Sequence similarities
    Belongs to the calsequestrin family.
  • Cellular localization
    Sarcoplasmic reticulum lumen. Mitochondrion. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Also mitochondrial according to PubMed:7945294.
  • Information by UniProt
  • Database links
  • Alternative names
    • Calmitin antibody
    • Calmitine antibody
    • Calsequestrin 1 (fast twitch, skeletal muscle) antibody
    • Calsequestrin antibody
    • Calsequestrin, cell antibody
    • Calsequestrin, skeletal muscle isoform antibody
    • Calsequestrin-1 antibody
    • CASQ antibody
    • Casq1 antibody
    • CASQ1_HUMAN antibody
    • PDIB1 antibody
    • skeletal muscle isoform antibody
    see all

Images

  • Anti-Calsequestrin 1 antibody (ab126241) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 44 kDa
  • Anti-Calsequestrin 1 antibody (ab126241) at 1/1000 dilution + Mouse heart whole cell lysate at 50 µg

    Predicted band size : 44 kDa

References

ab126241 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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I regret to inform you that the originator of this antibody no longer has sufficient stocks for us to be able to make this product available to our customers. We have therefore been forced to withdraw abab126241 fr...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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