Overview

  • Product name
  • Description
    Rabbit polyclonal to CAMK1D
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Zebrafish
  • Immunogen

    Recombinant fragment, corresponding to a sequence within amino acids 1-355 of Human CAMK1D (AAH35745).

  • Positive control
    • WB: 293T, HeLaS3, HepG2, MOLT4 or Raji whole cell lysate; ICC/IF: HeLa cells; IHC-P: OVCAR3 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab97803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 43 kDa.
IHC-P Use at an assay dependent concentration.
ICC/IF 1/100 - 1/200.

Target

  • Function
    Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
  • Tissue specificity
    Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Domain
    The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • Cellular localization
    Cytoplasm. Nucleus. Predominantly cytoplasmic (Probable). Also nuclear upon activation.
  • Information by UniProt
  • Database links
  • Alternative names
    • A630059D12Rik antibody
    • Calcium/calmodulin dependent protein kinase ID antibody
    • Calcium/calmodulin dependent protein kinase type 1D antibody
    • Calcium/calmodulin-dependent protein kinase I-delta antibody
    • Calcium/calmodulin-dependent protein kinase type 1D antibody
    • CaM K1 antibody
    • CaM KI delta antibody
    • CaM kinase I delta antibody
    • CaM kinase ID antibody
    • CaM-KI delta antibody
    • CAMK 1D antibody
    • CAMK1D antibody
    • CaMKI delta antibody
    • CamKI like protein kinase antibody
    • CamKI-like protein kinase antibody
    • CaMKID antibody
    • CKLiK antibody
    • E030025C11Rik antibody
    • KCC1D_HUMAN antibody
    • OTTHUMP00000019119 antibody
    • OTTHUMP00000019120 antibody
    • OTTHUMP00000045030 antibody
    • RP11 462F15.1 antibody
    see all

Images

  • Anti-CAMK1D antibody (ab97803) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

    Predicted band size : 43 kDa
  • Top: ab97803 at 1/200 dilution staining CAMK1D in PFA-fixed HeLa cells by immunofluorescence.
    Bottom: image merged with DNA probe.
  • ab97803 at 1/500 dilution staining CAMK1D in paraffin-embedded OVCAR3 xenograft by immunohistochemistry.

References

ab97803 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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