Overview

  • Product nameAnti-CaMKII alpha antibody
    See all CaMKII alpha primary antibodies
  • Description
    Goat polyclonal to CaMKII alpha
  • Specificityab111890 is expected to recognize both reported isoforms (NP_057065.2; NP_741960.1). This antibody does cross-react with CAMKII beta protein
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Dog
  • Immunogen

    Synthetic peptide, C-

    PRTAQSEETRVWHR

    , from the internal region of Human CaMKII alpha (NP_057065.2; NP_741960.1).

  • Positive control
    • Human adrenal tissue and Human brain (Cortex) tissue Mouse brain lysate and Human Brain (Cerebellum) lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab111890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 55, 65 kDa (predicted molecular weight: 54 kDa).
ELISA 1/64000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionCaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationCell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha CaMKII antibody
    • Calcium calmodulin dependent protein kinase II antibody
    • Calcium/calmodulin dependent protein kinase II alpha B subunit antibody
    • Calcium/calmodulin dependent protein kinase type II alpha chain antibody
    • Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha antibody
    • Calcium/calmodulin-dependent protein kinase II alpha antibody
    • Calcium/calmodulin-dependent protein kinase II-alpha antibody
    • Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody
    • Calcium/calmodulin-dependent protein kinase type IIA antibody
    • CaM kinase II alpha chain antibody
    • CaM kinase II alpha subunit antibody
    • CaM kinase II subunit alpha antibody
    • CaMK II alpha subunit antibody
    • CaMK-II subunit alpha antibody
    • Camk2a antibody
    • CAMKA antibody
    • CaMKII antibody
    • CaMKIINalpha antibody
    • EC 2.7.11.17 antibody
    • KCC2A_HUMAN antibody
    • KIAA0968 antibody
    • MGC123320 antibody
    • MGC139375 antibody
    • MGC155201 antibody
    • mKIAA0968 antibody
    • PK2CDD antibody
    • PKCCD antibody
    • R74975 antibody
    • zgc:112538 antibody
    • zgc:123320 antibody
    see all

Anti-CaMKII alpha antibody images

  • Anti-CaMKII alpha antibody (ab111890) at 0.1 µg/ml + Mouse brain lysate in RIPA buffer at 35 µg

    Predicted band size : 54 kDa
  • ab111890, at 3.75 µg/ml, staining CaMKII alpha in formalin fixed, paraffin embedded Human adrenal by Immunohistochemistry.
  • ab111890, at 3.75 µg/ml, staining CaMKII alpha in formalin fixed, paraffin embedded Human brain cortex by Immunohistochemistry.

References for Anti-CaMKII alpha antibody (ab111890)

ab111890 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"