CaMKII alpha (phospho T286) peptide (ab115237)

Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab115237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CaMKII alpha + CaMKII beta (phospho T286) antibody (ab91290)

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Alpha CaMKII
    • Calcium calmodulin dependent protein kinase II
    • Calcium/calmodulin dependent protein kinase II alpha B subunit
    • Calcium/calmodulin dependent protein kinase type II alpha chain
    • Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
    • Calcium/calmodulin-dependent protein kinase II alpha
    • Calcium/calmodulin-dependent protein kinase II-alpha
    • Calcium/calmodulin-dependent protein kinase type II subunit alpha
    • Calcium/calmodulin-dependent protein kinase type IIA
    • CaM kinase II alpha chain
    • CaM kinase II alpha subunit
    • CaM kinase II subunit alpha
    • CaMK II alpha subunit
    • CaMK-II subunit alpha
    • Camk2a
    • CAMKA
    • CaMKII
    • CaMKIINalpha
    • EC 2.7.11.17
    • KCC2A_HUMAN
    • KIAA0968
    • MGC123320
    • MGC139375
    • MGC155201
    • mKIAA0968
    • PK2CDD
    • PKCCD
    • R74975
    • zgc:112538
    • zgc:123320
    see all
  • FunctionCaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationCell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.
  • Information by UniProt

References for CaMKII alpha (phospho T286) peptide (ab115237)

ab115237 has not yet been referenced specifically in any publications.

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