Overview

  • Product nameCamptothecin
  • Species reactivity
    Induces apoptosis in Jurkat cells, Osteosarcoma and hepatoma cells
  • General notesThis product is provided at 2 mM in DMSO.

Properties

  • RelevanceCamptothecin binds reversibly to inhibit nuclear topoisomerase I and stabilizes the topoisomerase-DNA covalent complex. Camptothecin also inhibits Tat-mediated transcription of HIV-1. Jurkat, Osteosarcoma and Hepatoma cells apoptosis can be induced by Camptothecin.
  • Alternative names
    • Camptothecin

References for Camptothecin (ab39758)

ab39758 has not yet been referenced specifically in any publications.

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