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Goat polyclonal to Cannabinoid Receptor I
This antibody is expected to recognize both reported isoforms (NP_057167.2; NP_149421.2).
Predicted to work with:
Mouse, Cow, Cat, Dog, Human, Pig, Chimpanzee, Rhesus monkey
with a Cysteine residue linker, corresponding to internal sequence amino acids 77-91 of Human Cannabinoid Receptor I (NP_057167.2; NP_149421.2)
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 55, 70 kDa (predicted molecular weight: 53 kDa).
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
Belongs to the G-protein coupled receptor 1 family.
Information by UniProt
Cannabinoid receptor 1 antibody
Western blot - Anti-Cannabinoid Receptor I antibody (ab118286)
Anti-Cannabinoid Receptor I antibody (ab118286) at 0.3 µg/ml + Rat brain lysate at 35 µg
Developed using the ECL technique.
Predicted band size:
Observed band size:
55,70 kDa (
why is the actual band size different from the predicted?
The observed molecular weight corresponds to earlier findings in the literature with different antibodies.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"