Overview

  • Product nameAnti-CANT1 antibody
    See all CANT1 primary antibodies
  • Description
    Mouse monoclonal to CANT1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: ASQERYSEKD DERKGANLLL SASPDFGDIA VSHVGAVVPT HGFSSFKFIP NTDDQIIVAL KSEEDSGRVA SYIMAFTLDG RFLLPETKIG SVKYEGIEFI , corresponding to amino acids 302-401 of Human CANT1

Properties

Applications

Our Abpromise guarantee covers the use of ab57343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCalcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.
    • Tissue specificityWidely expressed.
    • Involvement in diseaseDefects in CANT1 are the cause of Desbuquois dysplasia (DBQD) [MIM:251450]. A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations.
    • Sequence similaritiesBelongs to the apyrase family.
    • Post-translational
      modifications
      N-glycosylated.
    • Cellular localizationEndoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Processed form: Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Apyrase antibody
      • Apyrase homolog antibody
      • Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase antibody
      • Calcium activated nucleotidase 1 antibody
      • CANT 1 antibody
      • CANT1 antibody
      • CANT1_HUMAN antibody
      • Putative MAPK activating protein PM09 antibody
      • Putative MAPK-activating protein PM09 antibody
      • Putative NF kappa B activating protein 107 antibody
      • Putative NF-kappa-B-activating protein 107 antibody
      • SCAN 1 antibody
      • SCAN-1 antibody
      • SHAPY antibody
      • Soluble Ca activated nucleotidase isozyme 1 antibody
      • Soluble calcium activated nucleotidase 1 antibody
      • Soluble calcium activated nucleotidase SCAN 1 antibody
      • Soluble calcium-activated nucleotidase 1 antibody
      see all

    Anti-CANT1 antibody images



    • Predicted band size : 45 kDa
      CANT1 antibody (ab57343) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    References for Anti-CANT1 antibody (ab57343)

    ab57343 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57343.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"