• Product name
  • Description
    Rabbit polyclonal to CANT1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Drosophila melanogaster, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 324-373 (SPDFGDIAVS HVGAVVPTHG FSSFKFIPNT DDQIIVALKS EEDSGRVASY) of human CANT1 (NP_620148).

  • Positive control
    • Transfected 293T cell lysate



Our Abpromise guarantee covers the use of ab84786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function
    Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.
  • Tissue specificity
    Widely expressed.
  • Involvement in disease
    Defects in CANT1 are the cause of Desbuquois dysplasia (DBQD) [MIM:251450]. A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations.
  • Sequence similarities
    Belongs to the apyrase family.
  • Post-translational
  • Cellular localization
    Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Processed form: Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apyrase antibody
    • Apyrase homolog antibody
    • Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase antibody
    • Calcium activated nucleotidase 1 antibody
    • CANT 1 antibody
    • CANT1 antibody
    • CANT1_HUMAN antibody
    • Putative MAPK activating protein PM09 antibody
    • Putative MAPK-activating protein PM09 antibody
    • Putative NF kappa B activating protein 107 antibody
    • Putative NF-kappa-B-activating protein 107 antibody
    • SCAN 1 antibody
    • SCAN-1 antibody
    • SHAPY antibody
    • Soluble Ca activated nucleotidase isozyme 1 antibody
    • Soluble calcium activated nucleotidase 1 antibody
    • Soluble calcium activated nucleotidase SCAN 1 antibody
    • Soluble calcium-activated nucleotidase 1 antibody
    see all

Anti-CANT1 antibody images

  • Anti-CANT1 antibody (ab84786) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 45 kDa
    Observed band size : 42 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 44 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CANT1 antibody (ab84786)

ab84786 has not yet been referenced specifically in any publications.

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