Anti-CAPZB antibody [1H1] (ab122980)

Overview

  • Product nameAnti-CAPZB antibody [1H1]
    See all CAPZB primary antibodies
  • Description
    Mouse monoclonal [1H1] to CAPZB
  • Tested applicationsSuitable for: Sandwich ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (GST-tag) corresponding to Human CAPZB aa 192-272.

  • Positive control
    • Human Spleen tissue Human Testis tissue HeLa cells lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionF-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
  • Sequence similaritiesBelongs to the F-actin-capping protein beta subunit family.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • 11 antibody
    • Cap protein, actin, beta antibody
    • Cap Z antibody
    • CAPB antibody
    • CAPPB antibody
    • Capping protein (actin filament) muscle Z line beta antibody
    • Capping protein beta 2 antibody
    • CAPZ antibody
    • CapZ beta antibody
    • Capzb antibody
    • CAPZB_HUMAN antibody
    • DKFZp686K0524 antibody
    • F actin capping protein beta subunit antibody
    • F-actin-capping protein subunit beta antibody
    • FLJ12274 antibody
    • FLJ44693 antibody
    • MGC104401 antibody
    • MGC129749 antibody
    • MGC129750 antibody
    • wu:fk65f06 antibody
    • zgc:66149 antibody
    see all

Anti-CAPZB antibody [1H1] images

  • Immunohistochemistry of Formalin-Fixed, Paraffin-Embedded Human Spleen tissue with ab122980 at 5 µg/ml.
  • Immunohistochemistry of Formalin-Fixed, Paraffin-Embedded Human Testis tissue with ab122980 at 5 µg/ml.
  • Anti-CAPZB antibody [1H1] (ab122980) + HeLa cells lysate

    Predicted band size : 31 kDa
  • Detection limit for recombinant tagged CAPZB is approximately 0.1ng/ml as a capture antibody.

References for Anti-CAPZB antibody [1H1] (ab122980)

ab122980 has not yet been referenced specifically in any publications.

Product Wall

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The antibody we discussed, ab98698, is an appropriate antibody for detection of the anti-CAPZB antibody, ab122980.

Click here (or use the following: http://www.abcam.com/index.html?datasheet=98698). Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"