General notesab94201 is a 293T cell transfected lysate in which Human CAPZB has been transiently over-expressed using a pCMV-CAPZB plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more detailed how the transfected lysate was prepared view preparation notes
BackgroundFunction: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Similarity: Belongs to the F-actin-capping protein beta subunit family.