Overview

  • Product nameAnti-carabin antibody
    See all carabin primary antibodies
  • Description
    Rabbit polyclonal to carabin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within the N terminal amino acids 2-51 (AQALGEDLVQ PPELQDDSSS LGSDSELSGP GPYRQADRYG FIGGSSAEPG) of Human carabin (NP_940919).

  • Positive control
    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90153 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionInhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.
  • Tissue specificityMost abundant in spleen and peripheral blood leukocytes.
  • Sequence similaritiesContains 1 Rab-GAP TBC domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1810062O14Rik antibody
    • AI428527 antibody
    • Carabin antibody
    • FLJ00332 antibody
    • MGC46488 antibody
    • RGD1311490 antibody
    • TB10C_HUMAN antibody
    • TBC1 domain family member 10C antibody
    • TBC1D10C antibody
    see all

Anti-carabin antibody images

  • Anti-carabin antibody (ab90153) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 50 kDa

References for Anti-carabin antibody (ab90153)

ab90153 has not yet been referenced specifically in any publications.

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