Anti-Carbonic Anhydrase IX antibody (ab15086)

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ab15086 has been referenced in 60 publications.

  • Veyrat M  et al. Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells. Oncotarget 7:82580-82593 (2016). IHC-P ; Human . PubMed: 27791989
  • Eom KY  et al. The Expression of Carbonic Anhydrase (CA) IX/XII and Lymph Node Metastasis in Early Breast Cancer. Cancer Res Treat 48:125-32 (2016). IHC-P ; Human . PubMed: 25761481
  • Ning XH  et al. Association between FBP1 and hypoxia-related gene expression in clear cell renal cell carcinoma. Oncol Lett 11:4095-4098 (2016). PubMed: 27313747
  • Szendroi A  et al. Opposite prognostic roles of HIF1a and HIF2a expressions in bone metastatic clear cell renal cell cancer. Oncotarget 7:42086-42098 (2016). IHC . PubMed: 27244898
  • Morais-Santos F  et al. Targeting lactate transport suppresses in vivo breast tumour growth. Oncotarget 6:19177-89 (2015). IHC . PubMed: 26203664
  • Pinheiro C  et al. Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors. Oncotarget 6:44403-21 (2015). PubMed: 26587828
  • Abraham S  et al. A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. Nat Commun 6:7286 (2015). PubMed: 26129894
  • Kim JI  et al. Expression of hypoxic markers and their prognostic significance in soft tissue sarcoma. Oncol Lett 9:1699-1706 (2015). IHC ; Human . PubMed: 25789026
  • Friedman GK  et al. ?134.5-deleted HSV-1-expressing human cytomegalovirus IRS1 gene kills human glioblastoma cells as efficiently as wild-type HSV-1 in normoxia or hypoxia. Gene Ther 22:348-55 (2015). PubMed: 25427614
  • Verduzco D  et al. Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. PLoS One 10:e0120958 (2015). PubMed: 25811878
  • Lee JG  et al. Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions. Respir Res 16:138 (2015). IHC ; Human . PubMed: 26553068
  • Pertega-Gomes N  et al. A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy. J Pathol 236:517-30 (2015). IHC ; Human . PubMed: 25875424
  • Wojtkowiak JW  et al. Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302. Cancer Metab 3:2 (2015). IHC-P ; Mouse . PubMed: 25635223
  • Iwasaki K  et al. Role of hypoxia-inducible factor-1a, carbonic anhydrase-IX, glucose transporter-1 and vascular endothelial growth factor associated with lymph node metastasis and recurrence in patients with locally advanced cervical cancer. Oncol Lett 10:1970-1978 (2015). IHC-P ; Human . PubMed: 26622782
  • Pappa KI  et al. Comparative assessment of lymph node micrometastasis in cervical, endometrial and vulvar cancer: insights on the real time qRT-PCR approach versus immunohistochemistry, employing dual molecular markers. Biomed Res Int 2014:187684 (2014). IHC . PubMed: 24527437
  • Larrayoz M  et al. Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype. EMBO Mol Med 6:539-50 (2014). IHC-P . PubMed: 24500694
  • Bodempudi V  et al. miR-210 promotes IPF fibroblast proliferation in response to hypoxia. Am J Physiol Lung Cell Mol Physiol 307:L283-94 (2014). PubMed: 24951777
  • Williamson SR  et al. Renal cell carcinoma with angioleiomyoma-like stroma: clinicopathological, immunohistochemical, and molecular features supporting classification as a distinct entity. Mod Pathol N/A:N/A (2014). PubMed: 25189644
  • Sousa B  et al. The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype. BMC Cancer 14:734 (2014). WB, Flow Cyt ; Human . PubMed: 25269858
  • Jiwa LS  et al. Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases. BMC Cancer 14:864 (2014). IHC . PubMed: 25417118
  • Afonso J  et al. CD147 and MCT1-potential partners in bladder cancer aggressiveness and cisplatin resistance. Mol Carcinog N/A:N/A (2014). PubMed: 25263481
  • Chang J  et al. Hypoxia modulates the phenotype of osteoblasts isolated from knee osteoarthritis patients, leading to undermineralized bone nodule formation. Arthritis Rheumatol 66:1789-99 (2014). IHC . PubMed: 24574272
  • Silén J  et al. Uptake of [(18)F]EF5 as a Tracer for Hypoxic and Aggressive Phenotype in Experimental Head and Neck Squamous Cell Carcinoma. Transl Oncol N/A:N/A (2014). PubMed: 24862538
  • Kim JH  et al. Expression of carbonic anhydrase IX in human fetal joints, ligaments and tendons: a potential marker of mechanical stress in fetal development? Anat Cell Biol 46:272-84 (2013). PubMed: 24386600
  • Mayer A  et al. Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix. Br J Cancer 108:402-8 (2013). IHC . PubMed: 23322209
  • Granja S  et al. The monocarboxylate transporter inhibitor a-cyano-4-hydroxycinnamic acid disrupts rat lung branching. Cell Physiol Biochem 32:1845-56 (2013). IHC . PubMed: 24356196
  • Figueras A  et al. The impact of KRAS mutations on VEGF-A production and tumour vascular network. BMC Cancer 13:125 (2013). IHC-P ; Mouse . PubMed: 23506169
  • Rathman-Josserand M  et al. Human hair follicle stem/progenitor cells express hypoxia markers. J Invest Dermatol 133:2094-7 (2013). IHC ; Human . PubMed: 23474947
  • van der Groep P  et al. HIF-1a overexpression in ductal carcinoma in situ of the breast in BRCA1 and BRCA2 mutation carriers. PLoS One 8:e56055 (2013). IHC-P ; Human . PubMed: 23409121
  • Salman S  et al. Chronic exposure of neonatal rat adrenomedullary chromaffin cells to opioids in vitro blunts both hypoxia and hypercapnia chemosensitivity. J Physiol 591:515-29 (2013). PubMed: 23148319
  • Vermeulen JF  et al. Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer. PLoS One 8:e53353 (2013). IHC-P ; Human . PubMed: 23308200
  • Ilie M  et al. Response of CAIX and CAXII to in vitro re-oxygenation and clinical significance of the combined expression in NSCLC patients. Lung Cancer 82:16-23 (2013). PubMed: 23910904
  • Klimowicz AC  et al. The prognostic impact of a combined carbonic anhydrase IX and Ki67 signature in oral squamous cell carcinoma. Br J Cancer 109:1859-66 (2013). IHC-P ; Human . PubMed: 24008660
  • Bicker A  et al. Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer. Hum Mol Genet N/A:N/A (2013). PubMed: 24026678
  • Cimino J  et al. Towards lipidomics of low-abundant species for exploring tumor heterogeneity guided by high-resolution mass spectrometry imaging. Int J Mol Sci 14:24560-80 (2013). IHC-Fr . PubMed: 24351834
  • Vermeulen JF  et al. Immunophenotyping invasive breast cancer: paving the road for molecular imaging. BMC Cancer 12:240 (2012). IHC . PubMed: 22695343
  • Cárdenas-Rodríguez J  et al. Imaging biomarkers to monitor response to the hypoxia-activated prodrug TH-302 in the MiaPaCa2 flank xenograft model. Magn Reson Imaging 30:1002-9 (2012). PubMed: 22554971
  • Rahimi AS  et al. p16, Cyclin D1, and HIF-1a Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy. Int J Otolaryngol 2012:685951 (2012). IHC . PubMed: 22888357
  • Wojtkowiak JW  et al. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. Cancer Res 72:3938-47 (2012). PubMed: 22719070
  • Niccoli S  et al. The Asian-American E6 variant protein of human papillomavirus 16 alone is sufficient to promote immortalization, transformation, and migration of primary human foreskin keratinocytes. J Virol 86:12384-96 (2012). PubMed: 22951839
  • Smeland E  et al. Prognostic impacts of hypoxic markers in soft tissue sarcoma. Sarcoma 2012:541650 (2012). IHC-P ; Human . PubMed: 22454562
  • Thrall DE  et al. Thermal dose fractionation affects tumour physiological response. Int J Hyperthermia 28:431-40 (2012). PubMed: 22804741
  • von Teichman A  et al. VHL mutations and dysregulation of pVHL- and PTEN-controlled pathways in multilocular cystic renal cell carcinoma. Mod Pathol 24:571-8 (2011). PubMed: 21151099
  • Lakhal S  et al. Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors: NEW LINK BETWEEN HYPOXIA SIGNALING AND IRON HOMEOSTASIS. J Biol Chem 286:4090-7 (2011). PubMed: 20966077
  • Kondo Y  et al. Clinicopathological significance of carbonic anhydrase 9, glucose transporter-1, Ki-67 and p53 expression in oral squamous cell carcinoma. Oncol Rep 25:1227-33 (2011). PubMed: 21399882
  • Brockton N  et al. High stromal carbonic anhydrase IX expression is associated with decreased survival in P16-negative head-and-neck tumors. Int J Radiat Oncol Biol Phys 80:249-57 (2011). IHC-P ; Human . PubMed: 21300470
  • Ameri K  et al. Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype. Br J Cancer 102:561-9 (2010). WB ; Human . PubMed: 20051957
  • Lancashire LJ  et al. A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks. Breast Cancer Res Treat 120:83-93 (2010). Human . PubMed: 19347577
  • Ilie M  et al. High levels of carbonic anhydrase IX in tumour tissue and plasma are biomarkers of poor prognostic in patients with non-small cell lung cancer. Br J Cancer : (2010). IHC-P ; Human . PubMed: 20461082
  • Tailor TD  et al. Effect of pazopanib on tumor microenvironment and liposome delivery. Mol Cancer Ther 9:1798-808 (2010). IHC-Fr ; Mouse . PubMed: 20515941
  • Skowronski K  et al. Ischemia dysregulates DNA methyltransferases and p16(INK4a) methylation in human colorectal cancer cells. Epigenetics 5: (2010). IHC-P ; Human . PubMed: 20543577
  • Blank A  et al. SDHB loss predicts malignancy in pheochromocytomas/sympathethic paragangliomas, but not through hypoxia signalling. Endocr Relat Cancer 17:919-28 (2010). IHC-P ; Human . PubMed: 20702724
  • Tennant DA  et al. Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death. Oncogene 28:4009-21 (2009). IHC-P ; Human . PubMed: 19718054
  • Qayum N  et al. Tumor vascular changes mediated by inhibition of oncogenic signaling. Cancer Res 69:6347-54 (2009). IHC . PubMed: 19622766
  • Gimelli S  et al. The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma. Mol Cancer 8:52 (2009). IHC-P ; Human . PubMed: 19642973
  • Korkeila E  et al. Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer. Br J Cancer 100:874-80 (2009). WB, IHC-P ; Human . PubMed: 19240720
  • Schmitt AM  et al. VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors. Endocr Relat Cancer 16:1219-27 (2009). PubMed: 19690016
  • Eardley KS  et al. The role of capillary density, macrophage infiltration and interstitial scarring in the pathogenesis of human chronic kidney disease. Kidney Int 74:495-504 (2008). PubMed: 18528327
  • Fleckenstein K  et al. Temporal onset of hypoxia and oxidative stress after pulmonary irradiation. Int J Radiat Oncol Biol Phys 68:196-204 (2007). PubMed: 17448873
  • Jackson IL  et al. Superoxide dismutase mimetic reduces hypoxia-induced O2*-, TGF-beta, and VEGF production by macrophages. Free Radic Res 41:8-14 (2007). PubMed: 17164174

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