Anti-Carboxymethyl Lysine antibody (Biotin) (ab27685)

Overview

  • Product nameAnti-Carboxymethyl Lysine antibody (Biotin)
    See all Carboxymethyl Lysine primary antibodies
  • Description
    Goat polyclonal to Carboxymethyl Lysine (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Species independent
  • Immunogen

    Carboxy methyl Lysine conjugated to KLH.

Properties

Applications

Our Abpromise guarantee covers the use of ab27685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/2500 - 1/20000.
    WB: 1/2500 - 1/20000.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceN epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.
    • Alternative names
      • CML antibody
      • N Epsilon (Carboxymethyl) Lysine antibody

    References for Anti-Carboxymethyl Lysine antibody (Biotin) (ab27685)

    ab27685 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"