Anti-Carboxymethyl Lysine antibody (HRP) (ab27686)

Overview

  • Product nameAnti-Carboxymethyl Lysine antibody (HRP)
    See all Carboxymethyl Lysine primary antibodies
  • Description
    Goat polyclonal to Carboxymethyl Lysine (HRP)
  • ConjugationHRP
  • SpecificityThis antibody specifically binds to Carboxy Methyl Lysine modified proteins.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Species independent
  • Immunogen

    Carboxy methyl Lysine conjugated to KLH.

  • General notes


    The concentration of protein and buffer salts will decrease to one half of the original after the addition of glycerol.

Properties

Applications

Our Abpromise guarantee covers the use of ab27686 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000 - 1/4000.
WB 1/1000 - 1/4000. Predicted molecular weight: 1 kDa.

Target

  • RelevanceN epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.
  • Alternative names
    • CML antibody
    • N Epsilon (Carboxymethyl) Lysine antibody

References for Anti-Carboxymethyl Lysine antibody (HRP) (ab27686)

ab27686 has not yet been referenced specifically in any publications.

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