Anti-Carboxypeptidase B2 antibody (ab83809)


  • Product nameAnti-Carboxypeptidase B2 antibody
    See all Carboxypeptidase B2 primary antibodies
  • Description
    Rabbit polyclonal to Carboxypeptidase B2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 324-373 (RSKSKDHEEL SLVASEAVRA IEKTSKNTRY THGHGSETLY LAPGGGDDWI) of Human Carboxypeptidase B2 (NP_001863).

  • Positive control
    • Human fetal heart lysate.



Our Abpromise guarantee covers the use of ab83809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/1562500.


  • RelevanceThis protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues; pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5 – 10 µg/ml. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • 1110032P04Rik antibody
    • 4930405E17Rik antibody
    • bA139H14.2 antibody
    • Carboxypeptidase B like protein antibody
    • Carboxypeptidase U antibody
    • CarboxypeptidaseB2 antibody
    • CarboxypeptidaseU antibody
    • CP B2 antibody
    • CPB 2 antibody
    • CPB2 antibody
    • CPU antibody
    • PCPB antibody
    • Plasma carboxypeptidase B antibody
    • Plasma carboxypeptidase B2 antibody
    • Procarboxypeptidase B antibody
    • Procarboxypeptidase R antibody
    • Procarboxypeptidase U antibody
    • TAFI antibody
    • Thrombin activable fibrinolysis inhibitor antibody
    • Thrombin activatable fibrinolysis inhibitor antibody
    see all

Anti-Carboxypeptidase B2 antibody images

  • Anti-Carboxypeptidase B2 antibody (ab83809) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 48 kDa
    Observed band size : 44 kDa (why is the actual band size different from the predicted?)

References for Anti-Carboxypeptidase B2 antibody (ab83809)

ab83809 has not yet been referenced specifically in any publications.

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