Anti-Carboxypeptidase Y antibody (HRP) (ab34646)

Overview

  • Product nameAnti-Carboxypeptidase Y antibody (HRP)
    See all Carboxypeptidase Y primary antibodies
  • Description
    Rabbit polyclonal to Carboxypeptidase Y (HRP)
  • ConjugationHRP
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with Bakers Yeast.
  • Immunogen

    Carboxypeptidase Y [Baker's Yeast]

  • General notes


    Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified Carboxypeptidase Y [Baker’s Yeast]. Cross reactivity against Carboxypeptidase Y from other sources may occur but has not been specifically determined.

Properties

Applications

Our Abpromise guarantee covers the use of ab34646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Target

  • FunctionInvolved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.
  • Sequence similaritiesBelongs to the peptidase S10 family.
  • Post-translational
    modifications
    Enters the endoplasmic reticulum as an inactive zymogen and is modified by four N-linked core oligosaccharides, giving rise to a precursor known as P1 (67 kDa). As P1 transits through the Golgi, extension of its core oligosaccharides leads to the Golgi-modified P2 precursor (69 kDa). P2 is sorted away from secretory proteins at or beyond a late Golgi compartment and is subsequently delivered to the vacuole via a prevacuolar endosome-like compartment. Upon arrival in the vacuole, the N-terminal prosegment of P2 is cleaved to yield the enzymatically active mature vacuolar form of CPY (61 kDa).
  • Cellular localizationVacuole. Lysosome-like vacuoles.
  • Information by UniProt
  • Alternative names
    • carboxypeptidase C PRC1 antibody
    • Carboxypeptidase Y antibody
    • Carboxypeptidase YSCY antibody
    • CBPY_YEAST antibody
    • CPY antibody
    • LBC1 antibody
    • PRC1 antibody
    • Vacuolar carboxypeptidase Y antibody
    see all

References for Anti-Carboxypeptidase Y antibody (HRP) (ab34646)

ab34646 has not yet been referenced specifically in any publications.

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