Anti-Carboxypeptidase Z antibody - N-terminal (ab91180)

Overview

  • Product name
    Anti-Carboxypeptidase Z antibody - N-terminal
  • Description
    Rabbit polyclonal to Carboxypeptidase Z - N-terminal
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) conjugated to KLH from the N-terminus (NP_001014447)

  • Positive control
    • K562 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 74 kDa.
ELISA 1/1000.

Target

  • Relevance
    Carboxypeptidase Z is a member of the metallocarboxypeptidase family and displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Carboxypeptidase Z probably modulates the Wnt signaling pathway, by cleaving some undefined protein and may play a role in cleavage during prohormone processing. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • CBPZ antibody
    • CPZ antibody
    • EC=3.4.17.- antibody
    • MGC99682 antibody

Images

  • Anti-Carboxypeptidase Z antibody - N-terminal (ab91180) at 1/50 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 74 kDa

References

ab91180 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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