Anti-Carcino Embryonic Antigen CEA antibody [26/5/1] (ab26285)

Overview

  • Product nameAnti-Carcino Embryonic Antigen CEA antibody [26/5/1]
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description
    Mouse monoclonal [26/5/1] to Carcino Embryonic Antigen CEA
  • SpecificityAb26285 recognizes exclusively CEACAM5 transiently expressed on the cell surface of transfected BOSC cells. It can be used to distinguish CEACAM5 from all other CEACAM and probably all pregnancy specific glycoproteins molecules, namely CEACAM1 (BGP/CD66a), CEACAM3 (CGM1/CD66d), CEACAM4 (CGM7), CEACAM6 (NCA/CD66c), CEACAM7 (CGM2), CEACAM8 (CGM6/CD66b) and PSG1 (CD66f) based on its reactivity pattern with stable HeLa transfectants expressing individual CEA family members.
  • Tested applicationsSuitable for: Flow Cyt, ELISA, IHC-Fr, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Ab26285 was generated by immunization of BALB/c mice with a CEA partially purified from a perchloric acid extract from liver metastases of colonic tumors.

Properties

Applications

Our Abpromise guarantee covers the use of ab26285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
ELISA
IHC-Fr
ICC/IF
WB
  • Application notesELISA: Use at an assay dependent dilution.
    Flow Cyt: Use at an assay dependent dilution.
    IF: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 77 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • Tissue specificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • Post-translational
      modifications
      Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    References for Anti-Carcino Embryonic Antigen CEA antibody [26/5/1] (ab26285)

    ab26285 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"