Anti-Carcino Embryonic Antigen CEA antibody (ab33562)

Overview

  • Product nameAnti-Carcino Embryonic Antigen CEA antibody
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description
    Rabbit polyclonal to Carcino Embryonic Antigen CEA
  • SpecificityRecognizes human CEA and CEA like proteins such as non specific crossreacting antigen (NCA), NCA2, and biliary glycoprotein (BGP1). Has been absorbed with plasma proteins and blood group antigens A and B.
  • Tested applicationsSuitable for: IP, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Does not react with: Dog
  • Immunogen

    Human Carcino Embryonic Antigen CEA isolated from hepatic metastasis of colon adenocarcinoma

  • Positive control
    • LS174T cells or colon carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab33562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
WB 1/200. Predicted molecular weight: 77 kDa.
IHC-P 1/500 - 1/1000. Antigen retrieval is not essential but may optimise staining.

Target

  • FunctionCell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
  • Tissue specificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Carcinoembryonic antigen antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
    • CD66e antibody
    • CEA antibody
    • Ceacam5 antibody
    • CEAM5_HUMAN antibody
    • DKFZp781M2392 antibody
    • Meconium antigen 100 antibody
    • OTTHUMP00000199032 antibody
    • OTTHUMP00000199033 antibody
    • OTTHUMP00000199034 antibody
    see all

References for Anti-Carcino Embryonic Antigen CEA antibody (ab33562)

This product has been referenced in:
  • Graham SA  et al. Identification of Neutrophil Granule Glycoproteins as Lewisx-containing Ligands Cleared by the Scavenger Receptor C-type Lectin. J Biol Chem 286:24336-49 (2011). WB ; Human . Read more (PubMed: 21561871) »

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Rat Tissue sections (liver)
Specification liver
Fixative Acetone
Permeabilization No
Username

Dr. Krause

Verified customer

Submitted Feb 08 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"