The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesIHC-P: 1/200 for 10 min at RT. No special pre-treatment is required for the immunohistochemical staining of formalin/paraffin tissues.
WB: Use at an assay dependent dilution. Predicted molecular weight: 77 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionCell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
Tissue specificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family. Contains 7 Ig-like (immunoglobulin-like) domains.
Post-translational modificationsComplex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.