Anti-Carcino Embryonic Antigen CEA antibody [Col-1], prediluted (ab17238)

Overview

  • Product nameAnti-Carcino Embryonic Antigen CEA antibody [Col-1], prediluted
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description
    Mouse monoclonal [Col-1] to Carcino Embryonic Antigen CEA, prediluted
  • SpecificityThis antibody reacts with a highly glycosylated protein of MW 180 kD, synthesized during development in the fetal gut and several tumors. It does not react with normal colon antigen (NCA). It stains the cell surface and cytoplasm of malignant glands in colorectal adenocarcinomas.
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    BALB/C mice were injected with extract of colon carcinoma cells.

  • Positive control
    • Colon carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab17238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notesIHC-P: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution (acetone fixed sections).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • Tissue specificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • Post-translational
      modifications
      Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    Anti-Carcino Embryonic Antigen CEA antibody [Col-1], prediluted images

    • ab17238 staining Carcino Embryonic Antigen CEA in human colon carcinoma tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    References for Anti-Carcino Embryonic Antigen CEA antibody [Col-1], prediluted (ab17238)

    ab17238 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"