Anti-Carcino Embryonic Antigen CEA antibody, prediluted (ab15157)

Overview

  • Product name
    Anti-Carcino Embryonic Antigen CEA antibody, prediluted
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description
    Rabbit polyclonal to Carcino Embryonic Antigen CEA, prediluted
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human) (Immunogen available as ab38226.)

  • Positive control
    • Colon carcinomas: ab15157 stains cytoplasm and lumenal membrane

Properties

Applications

Our Abpromise guarantee covers the use of ab15157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Working dilution, ready-to-use for 10 min at RT

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • Tissue specificity
      Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • Sequence similarities
      Belongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • Post-translational
      modifications
      Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    Images

    • ab15157 staining Carcino Embryonic Antigen CEA in Human stomach tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was blocked with 10% goat serum in PBS for 30 minutes; antigen retrieval was by heat mediation in a citrate buffer (pH 6.0). Samples were incubated with primary antibody (1/10 in PBS containing 1% BSA) overnight at 4°C. A HRP-conjugated anti-mouse IgG polyclonal was used as the secondary antibody. CEA was localized on the apical luminal surface of normal mucosa.

    References

    This product has been referenced in:
    • Zhou J  et al. Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 9:172 (2011). IHC-P ; Human . Read more (PubMed: 22195770) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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