Anti-Carcino Embryonic Antigen CEA antibody, prediluted (ab74665)

Overview

  • Product name
    Anti-Carcino Embryonic Antigen CEA antibody, prediluted
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description
    Rabbit polyclonal to Carcino Embryonic Antigen CEA, prediluted
  • Specificity
    ab74665 reacts with CEA and CEA-like proteins such as non-specific cross-reacting antigen (NCA), NCA2, and biliary glycoprotein (BGP1).
    ab74665 reacts weakly with Rat. We have data to indicate that this antibody may not cross react with Dog. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length Human Carcino Embryonic Antigen CEA protein isolated from hepatic metastasis of colon adenocarcinoma.

  • Positive control
    • Colon carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab74665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Ready to Use.
    No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • Tissue specificity
      Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • Sequence similarities
      Belongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • Post-translational
      modifications
      Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    Anti-Carcino Embryonic Antigen CEA antibody, prediluted images

    • Formalin-fixed, paraffin-embedded human colon carcinoma stained with ab74665, using peroxidase-conjugate and AEC chromogen. Note luminal surface and cytoplasmic staining of tumor cells.

    References for Anti-Carcino Embryonic Antigen CEA antibody, prediluted (ab74665)

    ab74665 has not yet been referenced specifically in any publications.

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