Overview

  • Product name
  • Description
    Rabbit polyclonal to CARD12
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to amino acids near the C terminus (Human).

  • Positive control
    • Human peripheral blood leukocyte cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab21301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 116 kDa).
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    Plays a role in the promotion of apoptosis.
  • Tissue specificity
    Isoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.
  • Sequence similarities
    Contains 1 CARD domain.
    Contains 14 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • Cellular localization
    Cytoplasm. Cytoplasmic filaments.
  • Information by UniProt
  • Database links
  • Alternative names
    • and NACHT-containing protein antibody
    • CARD 12 antibody
    • CARD antibody
    • CARD LRR and NACHT containing protein 1 antibody
    • CARD LRR and NACHT containing protein antibody
    • CARD12 antibody
    • Caspase recruitment domain containing protein 12 antibody
    • Caspase recruitment domain family member 12 antibody
    • Caspase recruitment domain-containing protein 12 antibody
    • CLAN 1 antibody
    • CLAN A antibody
    • CLAN antibody
    • CLAN B antibody
    • CLAN C antibody
    • CLAN D antibody
    • Clan protein antibody
    • CLAN1 antibody
    • CLANA antibody
    • CLANB antibody
    • CLANC antibody
    • CLAND antibody
    • CLR 2.1 antibody
    • CLR2.1 antibody
    • ICE protease activating factor antibody
    • Ice protease-activating factor antibody
    • Ipaf antibody
    • LRR antibody
    • NLR family CARD domain containing 4 antibody
    • NLR family CARD domain-containing protein 4 antibody
    • NLRC 4 antibody
    • NLRC4 antibody
    • NLRC4_HUMAN antibody
    • NOD like receptor C4 antibody
    • Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4 antibody
    • UNQ6189/PRO20215 antibody
    see all

Images

  • Lane 1 : Anti-CARD12 antibody (ab21301) at 0.5 µg/ml
    Lane 2 : Anti-CARD12 antibody (ab21301) at 1 µg/ml
    Lane 3 : Anti-CARD12 antibody (ab21301) at 2 µg/ml

    Lane 1 : Human PBL lysate 15ug
    Lane 2 : Human PBL lysate 15ug
    Lane 3 : Human PBL lysate 15ug


    Predicted band size : 116 kDa
  • ab21301 at 10µg/ml staining CARD12 in THP-1 cells by ICC/IF

References

ab21301 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab21301.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up