Overview

  • Product nameAnti-CARD8 antibody
    See all CARD8 primary antibodies
  • Description
    Rabbit polyclonal to CARD8
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 39-68 of Human CARD8

  • Positive control
    • HepG2 cell line lysates lung tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 49 kDa.
IHC-P 1/50 - 1/100. Heat-mediated/Sodium citrate pH6 is the method used for antigen retrieval.

Target

  • FunctionInhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.
  • Tissue specificityHigh expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow.
  • Sequence similaritiesContains 1 CARD domain.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptotic protein NDPP 1 antibody
    • Apoptotic protein NDPP1 antibody
    • CARD 8 antibody
    • CARD inhibitor of NF kappa B activating ligand antibody
    • CARD inhibitor of NF kappaB activating ligand antibody
    • CARD inhibitor of NF kappaB activating ligands antibody
    • CARD-inhibitor of NF-kappa-B-activating ligand antibody
    • CARD8 antibody
    • CARD8_HUMAN antibody
    • CARDINAL antibody
    • Caspase recruitment domain containing protein 8 antibody
    • Caspase recruitment domain family member 8 antibody
    • Caspase recruitment domain protein 8 antibody
    • Caspase recruitment domain-containing protein 8 antibody
    • DACAR antibody
    • Dakar antibody
    • DKFZp779L0366 antibody
    • FLJ18119 antibody
    • FLJ18121 antibody
    • KIAA0955 antibody
    • MGC57162 antibody
    • NDPP 1 antibody
    • NDPP antibody
    • NDPP1 antibody
    • TUCAN antibody
    • Tumor up regulated CARD containing antagonist of CASP9 antibody
    • Tumor up regulated CARD containing antagonist of caspase 9 antibody
    • Tumor up-regulated CARD-containing antagonist of CASP9 antibody
    • tumor up-regulated CARD-containing antagonist of caspase nine antibody
    • Tumor upregulated CARD containing antagonist of CASP9 antibody
    see all

Anti-CARD8 antibody images

  • Anti-CARD8 antibody (ab103488) at 1/100 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 49 kDa
  • IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. Using ab103488 at 1/50 dilution.

References for Anti-CARD8 antibody (ab103488)

ab103488 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"