Overview

  • Product nameAnti-Cardiotrophin 1 antibody
    See all Cardiotrophin 1 primary antibodies
  • Description
    Rabbit polyclonal to Cardiotrophin 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human Cardiotrophin 1.

    (Peptide available as ab99366.)

  • Positive control
    • This antibody gave a positive signal in HepG2 whole cell lysate as well as Cardiotrophin 1 active recombinant protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab83176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 21 kDa).

Target

  • FunctionInduces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
  • Tissue specificityHighly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.
  • Sequence similaritiesBelongs to the IL-6 superfamily.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cardiophin 1 antibody
    • Cardiophin1 antibody
    • Cardiotrophin I antibody
    • Cardiotrophin-1 antibody
    • Cardiotrophin1 antibody
    • CardiotrophinI antibody
    • CT 1 antibody
    • CT-1 antibody
    • CT1 antibody
    • CTF 1 antibody
    • Ctf1 antibody
    • CTF1_HUMAN antibody
    see all

Anti-Cardiotrophin 1 antibody images

  • All lanes : Anti-Cardiotrophin 1 antibody (ab83176) at 1 µg/ml

    Lane 1 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate at 10 µg
    Lane 2 : Recombinant Cardiotrophin 1 protein (ab9838) at 0.1 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 21 kDa
    Observed band size : 24 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 48 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 30 seconds

References for Anti-Cardiotrophin 1 antibody (ab83176)

ab83176 has not yet been referenced specifically in any publications.

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