Anti-CARHSP1 antibody (ab14245)
- Datasheet
- Specific References (1)
- Protocols
Overview
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Product nameAnti-CARHSP1 antibody
See all CARHSP1 primary antibodies -
DescriptionChicken polyclonal to CARHSP1
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Host speciesChicken
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Tested applicationsSuitable for: WB, ICC/IFmore details
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Species reactivityReacts with: Mouse, Rat, Human
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Immunogen
Synthetic peptide, corresponding to amino acids 1-147 of CARHSP1.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Storage bufferPreservative: None
Constituents: PBS -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgY
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Research areas
Applications
Our Abpromise guarantee covers the use of ab14245 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/2000. Predicted molecular weight: 16 kDa. | |
| ICC/IF | Use at an assay dependent dilution. PubMed: 21078874 |
Target
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FunctionBinds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro).
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Sequence similaritiesContains 1 CSD (cold-shock) domain.
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Post-translational
modificationsDephosphorylated by calcineurin in a Ca(2+) dependent manner. -
Cellular localizationCytoplasm. Cytoplasm > P-body. Cytoplasmic granule. Detected at cytoplasmic stress granules and P-bodies. Detected at exosome granules where mRNA is degraded.
- Information by UniProt
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Database links
- Entrez Gene: 23589 Human
- Entrez Gene: 100040232 Mouse
- Entrez Gene: 52502 Mouse
- Entrez Gene: 260416 Rat
- GenBank: NP_055131.2 Human
- SwissProt: Q9Y2V2 Human
- SwissProt: Q9CR86 Mouse
- SwissProt: Q9WU49 Rat
see all -
Alternative names
- Calcium regulated heat stable protein (24kD) antibody
- Calcium regulated heat stable protein 1 (24kD) antibody
- Calcium regulated heat stable protein 1 antibody
see all
Images
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Western blot - Anti-CARHSP1 antibody (ab14245)E coli derived fusion protein as test antigen. Ab14245 dilution: 1:2000 (0.5
µ g/ml). Colorimetric method for signal development.
E coli derived fusion protein as test antigen. Ab14245 dilution: 1:2000 (0.5µg/ml). Colorimetric method for signal development.
References
This product has been referenced in:
- Pfeiffer JR et al. CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes. Mol Cell Biol 31:277-86 (2011). WB, ICC/IF ; Mouse . Read more (PubMed: 21078874) »
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"