Overview

  • Product name
    Carvedilol
  • Description
    Potent β and α1 adrenoceptor antagonist
  • Biological description
    Potent β and α1 adrenoceptor antagonist (Ki values are 0.81, 0.96 and 2.2 nM for β1, β2 and α1 adrenoceptors, respectively). Shows antihypertensive, antioxidant, antiapoptotic, anti-inflammatory and antifibrotic properties.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Arozal W  et al. Carvedilol-Afforded Protection against Daunorubicin-Induced Cardiomyopathic Rats In Vivo: Effects on Cardiac Fibrosis and Hypertrophy. ISRN Pharmacol 2011:430549 (2011). Read more (PubMed: 22084713) »
  • Pönicke K  et al. Differential effects of bucindolol and carvedilol on noradenaline-induced hypertrophic response in ventricular cardiomyocytes of adult rats. J Pharmacol Exp Ther 301:71-6 (2002). Read more (PubMed: 11907159) »
  • Ruffolo RR  et al. The pharmacology of carvedilol. Eur J Clin Pharmacol 38 Suppl 2:S82-8 (1990). Read more (PubMed: 1974511) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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