Recombinant
RabMAb

Anti-Caspase-1 antibody [EPR4321] (ab108362)

Publishing research using ab108362? Please let us know so that we can cite the reference in this datasheet.

ab108362 has been referenced in 18 publications.

  • Donepudi AC  et al. Deficiency of cholesterol 7a-hydroxylase in bile acid synthesis exacerbates alcohol-induced liver injury in mice. Hepatol Commun 2:99-112 (2018). PubMed: 29404516
  • Zhang BC  et al. Luteolin alleviates NLRP3 inflammasome activation and directs macrophage polarization in lipopolysaccharide-stimulated RAW264.7 cells. Am J Transl Res 10:265-273 (2018). PubMed: 29423011
  • Gao J  et al. Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye. J Neuroinflammation 15:15 (2018). PubMed: 29329580
  • Zhang H  et al. AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality. J Immunol 198:4383-4393 (2017). PubMed: 28424239
  • Steen KA  et al. FABP4/aP2 Regulates Macrophage Redox Signaling and Inflammasome Activation via Control of UCP2. Mol Cell Biol 37:N/A (2017). WB ; Mouse . PubMed: 27795298
  • Guo W  et al. Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Nat Commun 8:2168 (2017). PubMed: 29255148
  • Giacoppo S  et al. Triggering of inflammasome by impaired autophagy in response to acute experimental Parkinson's disease: involvement of the PI3K/Akt/mTOR pathway. Neuroreport 28:996-1007 (2017). PubMed: 28902711
  • Ravindran R  et al. The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature 531:523-7 (2016). WB ; Mouse . PubMed: 26982722
  • Hu Z  et al. Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. Cell Death Dis 7:e2468 (2016). WB . PubMed: 27831552
  • Peng S  et al. Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-?B signaling and NLRP3 inflammasome activation. Oncotarget 7:80262-80274 (2016). PubMed: 27793052
  • Li Z  et al. Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC. Sci Rep 6:37447 (2016). PubMed: 27853287
  • Zhao J  et al. Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats. PLoS One 10:e0140772 (2015). WB ; Rat . PubMed: 26473731
  • Zhang X  et al. Porcine Mx1 fused to HIV Tat protein transduction domain (PTD) inhibits classical swine fever virus infection in vitro and in vivo. BMC Vet Res 11:264 (2015). Pig . PubMed: 26472464
  • Qi Y  et al. Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes. Invest Ophthalmol Vis Sci 55:5466-75 (2014). PubMed: 25097240
  • Zhen J  et al. AIM2 mediates inflammation-associated renal damage in hepatitis B virus-associated glomerulonephritis by regulating caspase-1, IL-1ß, and IL-18. Mediators Inflamm 2014:190860 (2014). WB ; Human . PubMed: 24701032
  • Maher K  et al. A role for stefin B (cystatin B) in inflammation and endotoxemia. J Biol Chem 289:31736-50 (2014). PubMed: 25288807
  • Dotson RJ  et al. Repression of inflammasome by Francisella tularensis during early stages of infection. J Biol Chem 288:23844-57 (2013). WB ; Mouse . PubMed: 23821549
  • Shi CS  et al. Activation of autophagy by inflammatory signals limits IL-1ß production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 13:255-63 (2012). PubMed: 22286270

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