Anti-Caspase-14 antibody [70A1426] (ab11920)

Overview

  • Product nameAnti-Caspase-14 antibody [70A1426]
    See all Caspase-14 primary antibodies
  • Description
    Mouse monoclonal [70A1426] to Caspase-14
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-14.
    Database link: P31944

  • Positive control
    • Mouse spleen cell extract.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThis antibody is affinity purified.
  • ClonalityMonoclonal
  • Clone number70A1426
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab11920 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 29.04 kDa).

Target

  • FunctionBelieved to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.
  • Tissue specificityExpressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.
  • Sequence similaritiesBelongs to the peptidase C14A family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptosis related cysteine protease antibody
    • CASP 14 antibody
    • CASP-14 antibody
    • CASP14 antibody
    • Caspase 14 apoptosis related cysteine protease antibody
    • Caspase 14 precursor antibody
    • Caspase-14 subunit p10 antibody
    • Caspase14 antibody
    • CASPE_HUMAN antibody
    • MGC119078 antibody
    • MGC119079 antibody
    • MICE antibody
    • Mini ICE antibody
    see all

Anti-Caspase-14 antibody [70A1426] images

References for Anti-Caspase-14 antibody [70A1426] (ab11920)

ab11920 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. This antibody was raised against a peptide corresponding to amino acids 2-18 of caspase 14, which is right in the pro-domain or including it (depending where the caspase 14 is processed, the first putative cleavage site bein...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"