Anti-Caspase-2 (phospho S157) antibody (ab62441)

Overview

  • Product nameAnti-Caspase-2 (phospho S157) antibody
    See all Caspase-2 primary antibodies
  • Description
    Rabbit polyclonal to Caspase-2 (phospho S157)
  • Specificityab62441 detects endogenous levels of Caspase-2 only when phosphorylated at serine 157.
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-2.
    Database link: P42575

  • Positive control
    • Human lung carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab62441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/10000.

Target

  • FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
  • Tissue specificityExpressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
  • Sequence similaritiesBelongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Post-translational
    modifications
    The mature protease can process its own propeptide, but not that of other caspases.
  • Information by UniProt
  • Database links
  • Alternative names
    • CASP 2 antibody
    • CASP-2 antibody
    • Casp2 antibody
    • CASP2_HUMAN antibody
    • Caspase 2 antibody
    • Caspase 2 apoptosis related cysteine peptidase antibody
    • Caspase-2 subunit p12 antibody
    • Caspase2 antibody
    • ICH 1 antibody
    • ICH 1 protease antibody
    • ICH 1L antibody
    • ICH1 antibody
    • ICH1 protease antibody
    • ICH1L antibody
    • NEDD-2 antibody
    • NEDD2 antibody
    • Neural precursor cell expressed developmentally down-regulated protein 2 antibody
    • PPP1R57 antibody
    • Protease ICH-1 antibody
    • Protein phosphatase 1 regulatory subunit 57 antibody
    see all

Anti-Caspase-2 (phospho S157) antibody images

  • Immunofluorescence analysis of Caspase-2 in human lung carcinoma tissue (paraffin section), using ab62441 (1:50); in the presence or absence of phosphopeptide.

References for Anti-Caspase-2 (phospho S157) antibody (ab62441)

ab62441 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"