Anti-Caspase-2L antibody [18E809] (ab13870)

Overview

  • Product nameAnti-Caspase-2L antibody [18E809]
    See all Caspase-2L primary antibodies
  • Description
    Mouse monoclonal [18E809] to Caspase-2L
  • SpecificityThis antibody is useful for detecting human Caspase-2 long form, which is about 48 kD.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-2L.
    Database link: P42575

  • Positive control
    • HL60 whole cell lysate.
  • General notes

    Stable for 6 months at 4 °C.

Properties

Applications

Our Abpromise guarantee covers the use of ab13870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 48 kDa.

Target

  • RelevanceFunction: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Tissue specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle. Similarity: Belongs to the peptidase C14A family. Contains 1 CARD domain. PTM: The mature protease can process its own propeptide, but not that of other caspases.
  • Database links
  • FormSpecific for P42575-1; the isoform that has been chosen as the 'canonical' sequence.
  • Alternative names
    • CASP2 antibody
    • ICH-1L antibody
    • ICH1 antibody
    • NEDD-2 antibody
    • NEDD2 antibody
    • Protease ICH-1 antibody
    see all

References for Anti-Caspase-2L antibody [18E809] (ab13870)

ab13870 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"