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Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.02% Sodium azide Constituent: PBS
Concentration information loading...
Purity Protein A purified
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 2 µg/ml.
Use a concentration of 1 µg/ml. Detects a band of approximately 40, 50 kDa.Can be blocked with
Human Caspase-2L peptide (ab39724).
Relevance Function: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Tissue specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Similarity: Belongs to the peptidase C14A family.
Contains 1 CARD domain.
PTM: The mature protease can process its own propeptide, but not that of other caspases.
Form Specific for P42575-1; the isoform that has been chosen as the 'canonical' sequence.
Anti-Caspase-2L antibody images
Western blot - Anti-Caspase-2L antibody (ab25896)
Lane 1 : Anti-Caspase-2L antibody (ab25896) at 0.5 µg/ml Lane 2 : Anti-Caspase-2L antibody (ab25896) at 1 µg/ml Lane 3 : Anti-Caspase-2L antibody (ab25896) at 2 µg/ml Lane 1 : Ramos cells Lane 2 : Ramos cells Lane 3 : Ramos cells Observed band size : 40,50 kDa ( why is the actual band size different from the predicted?)
Immunocytochemistry/ Immunofluorescence - Anti-Caspase-2L antibody (ab25896)
ab25896 at 2µg/ml staining Caspase-2L in A-20 cells by ICC/IF
References for Anti-Caspase-2L antibody (ab25896)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"