Overview

  • Product nameAnti-Caspase-6 antibody
    See all Caspase-6 primary antibodies
  • Description
    Rabbit polyclonal to Caspase-6
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein corresponding to Human Caspase-6 aa 1-293.
    Database link: P55212

  • Positive control
    • Mouse lung tissue lysate, Caspase-6 transfected 293T cell line lysate, HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab103570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 33 kDa.
ICC/IF 1/200.

Target

  • FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • Sequence similaritiesBelongs to the peptidase C14A family.
  • Post-translational
    modifications
    Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Anti-Caspase-6 antibody images

  • Anti-Caspase-6 antibody (ab103570) at 1/500 dilution + Mouse lung tissue lysate at 25 µg

    Predicted band size : 33 kDa
  • All lanes : Anti-Caspase-6 antibody (ab103570) at 1/500 dilution

    Lane 1 : Caspase 6 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 33 kDa
  • Proximity Ligation Analysis (PLA) of protein-protein interactions between CASP6 and APP.
    ab103570 at 1:200 dilution staining HeLa cells with anti-APP mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.

References for Anti-Caspase-6 antibody (ab103570)

ab103570 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"