Overview

  • Product nameAnti-Caspase-6 antibody
    See all Caspase-6 primary antibodies
  • Description
    Rabbit polyclonal to Caspase-6
  • SpecificityDetects endogenous levels of the large subunit of Caspase-6 resulting from cleavage at Asp162. This antibody does not recognize other cleaved caspases.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Rat Caspase-6 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). Synthetic peptide derived from the carboxy-terminal sequence of p18, the large subunit of rat caspase-6
    Database link: P55212

Properties

Applications

Our Abpromise guarantee covers the use of ab18520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB 1/1000. Predicted molecular weight: 20 kDa.

Target

  • FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • Sequence similaritiesBelongs to the peptidase C14A family.
  • Post-translational
    modifications
    Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

References for Anti-Caspase-6 antibody (ab18520)

ab18520 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"