Overview

  • Product nameAnti-Caspase-6 antibody
    See all Caspase-6 primary antibodies
  • Description
    Rabbit polyclonal to Caspase-6
  • SpecificityThis antibody recognizes a full length (35 kDa) and the cleaved fragment (15 kDa) of Caspase-6. The antibody specificity is confirmed by peptide inhibition studies.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Rat Caspase-6 (C terminal).
    Database link: P55212
    (Peptide available as ab38263)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab2552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Can be blocked with Caspase-6 peptide (ab38263).

Target

  • FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • Sequence similaritiesBelongs to the peptidase C14A family.
  • Post-translational
    modifications
    Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

References for Anti-Caspase-6 antibody (ab2552)

ab2552 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I can confirm that ab52295 and ab2552 are both rabbit polyclonals. They have also both been purified by affinity purification. So they are quite similar. However, I can confirm they are sourced from different places,...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"