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Product name Anti-Caspase-6 antibody [EPR4405] See all Caspase-6 primary antibodies
Rabbit monoclonal [EPR4405] to Caspase-6
Specificity ab108335 detects both the full length and cleaved forms of Caspase-6.
Tested applications Suitable for:
WB, IP, Flow Cyt more details Unsuitable for:
ICC or IHC-P
Mouse, Rat, Human
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human Caspase-6 aa 150-250.
Database link: P55212
Jurkat cells and cell lysate.
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb
® technology. RabMAb ® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
A trial size is available to purchase for this antibody.
Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage buffer PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purity Tissue culture supernatant
Clone number EPR4405
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 33 kDa.
1/10 - 1/100.
1/10 - 1/100.
ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
Application notes Is unsuitable for ICC or IHC-P.
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Sequence similarities Belongs to the peptidase C14A family.
Post-translational modifications Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
Cellular localization Cytoplasm.
Information by UniProt
Apoptotic protease Mch-2 antibody
Apoptotic protease MCH2 antibody
Anti-Caspase-6 antibody [EPR4405] images
References for Anti-Caspase-6 antibody [EPR4405] (ab108335)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"