Overview

  • Product nameAnti-Caspase-6 antibody [M378]
    See all Caspase-6 primary antibodies
  • Description
    Mouse monoclonal [M378] to Caspase-6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-6 (C terminal).
    Database link: P55212

  • Positive control
    • Human Jurkat, K562 and A431 cell lysates.
  • General notes

    Do not aliquot.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab119760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

Target

  • FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • Sequence similaritiesBelongs to the peptidase C14A family.
  • Post-translational
    modifications
    Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Anti-Caspase-6 antibody [M378] images

  • Lane 1 : Anti-Caspase 3 at 1/500 dilution
    Lane 2 : Anti-Caspase 3 at 1/1000 dilution
    Lane 3 : Anti-Caspase-6 antibody [M378] (ab119760) at 1/250 dilution
    Lane 4 : Anti-Caspase-6 antibody [M378] (ab119760) at 1/500 dilution
    Lane 5 : Anti-Caspase 7 at 1/500 dilution
    Lane 6 : Anti-Caspase 7 at 1/1000 dilution
    Lane 7 : Anti-Caspase 8 at 1/250 dilution
    Lane 8 : Anti-Caspase 8 at 1/500 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate
    Lane 3 : Jurkat cell lysate
    Lane 4 : Jurkat cell lysate
    Lane 5 : Jurkat cell lysate
    Lane 6 : Jurkat cell lysate
    Lane 7 : Jurkat cell lysate
    Lane 8 : Jurkat cell lysate


    Predicted band size : 33 kDa

References for Anti-Caspase-6 antibody [M378] (ab119760)

ab119760 has not yet been referenced specifically in any publications.

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