Validated using a knockout cell line

Anti-Caspase-9 antibody [E23] (ab32539)

Publishing research using ab32539? Please let us know so that we can cite the reference in this datasheet.

ab32539 has been referenced in 41 publications.

  • Yan H  et al. NR4A1-induced increase in the sensitivity of a human gastric cancer line to TNFa-mediated apoptosis is associated with the inhibition of JNK/Parkin-dependent mitophagy. Int J Oncol 52:367-378 (2018). PubMed: 29207128
  • Jin Q  et al. DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways. Redox Biol 14:576-587 (2018). PubMed: 29149759
  • Qiao H  et al. Liraglutide repairs the infarcted heart: The role of the SIRT1/Parkin/mitophagy pathway. Mol Med Rep 17:3722-3734 (2018). PubMed: 29328405
  • You S  et al. Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway. Mol Med Rep 17:4203-4212 (2018). PubMed: 29344654
  • Manousakidi S  et al. FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization. Oncogenesis 7:18 (2018). PubMed: 29467390
  • Liu X  et al. Long non-coding RNA Gas5 regulates proliferation and apoptosis in HCS-2/8 cells and growth plate chondrocytes by controlling FGF1 expression via miR-21 regulation. J Biomed Sci 25:18 (2018). PubMed: 29490650
  • Cai B  et al. MiR-16-5p targets SESN1 to regulate the p53 signaling pathway, affecting myoblast proliferation and apoptosis, and is involved in myoblast differentiation. Cell Death Dis 9:367 (2018). PubMed: 29511169
  • Yan H  et al. Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy. Oncol Rep 39:1671-1681 (2018). PubMed: 29436693
  • Lei Q  et al. Mitochonic acid 5 activates the MAPK-ERK-yap signaling pathways to protect mouse microglial BV-2 cells against TNFa-induced apoptosis via increased Bnip3-related mitophagy. Cell Mol Biol Lett 23:14 (2018). PubMed: 29636771
  • Wang MS  et al. Iron oxide magnetic nanoparticles combined with actein suppress non-small-cell lung cancer growth in a p53-dependent manner. Int J Nanomedicine 12:7627-7651 (2017). WB ; Human . PubMed: 29089760
  • Xu Z  et al. The protective effect of propofol against TNF-a-induced apoptosis was mediated via inhibiting iNOS/NO production and maintaining intracellular Ca2+homeostasis in mouse hippocampal HT22 cells. Biomed Pharmacother 91:664-672 (2017). PubMed: 28499237
  • Cheng P  et al. Molecular mechanisms of ampelopsin fromAmpelopsis megalophyllainduces apoptosis in HeLa cells. Oncol Lett 14:2691-2698 (2017). PubMed: 28928812
  • Masalova OV  et al. Modulation of Cell Death Pathways by Hepatitis C Virus Proteins in Huh7.5 Hepatoma Cells. Int J Mol Sci 18:N/A (2017). PubMed: 29113144
  • Zhang FQ  et al. Regulation of c-Jun N-Terminal Protein Kinase (JNK) Pathway in Apoptosis of Endothelial Outgrowth Cells Induced by Asymmetric Dimethylarginine. Med Sci Monit 23:2535-2542 (2017). WB ; Human . PubMed: 28546532
  • Li Y  et al. MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis. Cell Mol Biol Lett 22:3 (2017). WB . PubMed: 28536634
  • Gu L  et al. Polyphyllin I inhibits the growth of ovarian cancer cells in nude mice. Oncol Lett 12:4969-4974 (2016). PubMed: 28105203
  • Razavi BM  et al. Protective effect of crocin against apoptosis induced by subchronic exposure of the rat vascular system to diazinon. Toxicol Ind Health 32:1237-45 (2016). Rat . PubMed: 27353299
  • Zhu X  et al. Ziyuglycoside I Inhibits the Proliferation of MDA-MB-231 Breast Carcinoma Cells through Inducing p53-Mediated G2/M Cell Cycle Arrest and Intrinsic/Extrinsic Apoptosis. Int J Mol Sci 17:N/A (2016). Human . PubMed: 27879682
  • Guo H  et al. Nickel chloride-induced apoptosis via mitochondria- and Fas-mediated caspase-dependent pathways in broiler chickens. Oncotarget 7:79747-79760 (2016). IHC-P ; Chicken . PubMed: 27806327
  • Familtseva A  et al. Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-induced hypertension. Am J Physiol Cell Physiol 311:C596-C606 (2016). PubMed: 27488663
  • Liu ES  et al. c-Raf promotes angiogenesis during normal growth plate maturation. Development 143:348-55 (2016). IHC-P ; Mouse . PubMed: 26657770
  • Zhao X  et al. Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms. Mol Med Rep 14:1067-74 (2016). WB ; Human . PubMed: 27279418
  • He Q  et al. Lycopene attenuates inflammation and apoptosis in post-myocardial infarction remodeling by inhibiting the nuclear factor-?B signaling pathway. Mol Med Rep 11:374-8 (2015). Mouse . PubMed: 25323011
  • Aras AB  et al. Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats. Neural Regen Res 10:146-52 (2015). IHC-P ; Rat . PubMed: 25788936
  • Jiang S  et al. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells. PLoS One 10:e0132880 (2015). WB ; Human . PubMed: 26176608
  • Wang JF  et al. The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. Biomed Res Int 2014:582730 (2014). WB ; Human . PubMed: 24829906
  • Staudacher I  et al. HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells. PLoS One 9:e88164 (2014). WB ; Human . PubMed: 24516604
  • Iwasaki K  et al. Cytotoxic effects of the radiocontrast agent iotrolan and anesthetic agents bupivacaine and lidocaine in three-dimensional cultures of human intervertebral disc nucleus pulposus cells: identification of the apoptotic pathways. PLoS One 9:e92442 (2014). WB ; Human . PubMed: 24642945
  • Cui SX  et al. 13F-1, a novel 5-fluorouracil prodrug containing an Asn-Gly-Arg (NO2) COOCH3 tripeptide, inhibits human colonic carcinoma growth by targeting Aminopeptidase N (APN/CD13). Eur J Pharmacol 734:50-9 (2014). PubMed: 24726845
  • Brownhill S  et al. Proliferation Index: A Continuous Model to Predict Prognosis in Patients with Tumours of the Ewing's Sarcoma Family. PLoS One 9:e104106 (2014). IHC ; Human . PubMed: 25157404
  • Wang Y  et al. Targeting and eradicating hepatic cancer cells with a cancer-specific vector carrying the Buforin II gene. Cancer Biother Radiopharm 28:623-30 (2013). WB ; Human . PubMed: 24041444
  • Lu H  et al. The study of the Oxytropis kansuensis-induced apoptotic pathway in the cerebrum of SD rats. BMC Vet Res 9:217 (2013). Rat . PubMed: 24148892
  • Du LQ  et al. Radiation-sensitising effects of antennapedia proteins (ANTP)-SmacN7 on tumour cells. Int J Mol Sci 14:24087-96 (2013). WB ; Human . PubMed: 24336110
  • Fekkar A  et al. Secretome of human bronchial epithelial cells in response to the fungal pathogen Aspergillus fumigatus analyzed by differential in-gel electrophoresis. J Infect Dis 205:1163-72 (2012). WB ; Human . PubMed: 22357658
  • Yu E  et al. Structural Determinants of Caspase-9 Inhibition by the Vaccinia Virus Protein, F1L. J Biol Chem 286:30748-58 (2011). PubMed: 21757755
  • Khanna A  et al. Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice. Aging (Albany NY) 3:223-36 (2011). WB ; Mouse . PubMed: 21415464
  • Lv L  et al. Inhibition of peptidyl-prolyl cis/trans isomerase Pin1 induces cell cycle arrest and apoptosis in vascular smooth muscle cells. Apoptosis 15:41-54 (2010). WB ; Human . PubMed: 19904610
  • Altonsy MO  et al. Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enteropathogenic bacteria: mediation by the mitochondrial pathway. Int J Food Microbiol 137:190-203 (2010). WB ; Human . PubMed: 20036023
  • Zhang D  et al. Inhibition of pancreatic cancer cell proliferation by propranolol occurs through apoptosis induction: the study of beta-adrenoceptor antagonist's anticancer effect in pancreatic cancer cell. Pancreas 38:94-100 (2009). WB ; Human . PubMed: 19106745
  • Singh S  et al. CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth. Mol Cancer Ther 8:178-84 (2009). PubMed: 19139127
  • Chausiaux OE  et al. Hypogonadal mouse, a model to study the effects of the endogenous lack of gonadotropins on apoptosis. Biol Reprod 78:77-90 (2008). PubMed: 17671269


Sign up