Anti-Caspase-9 (phospho Y153) antibody (ab79202)


  • Product nameAnti-Caspase-9 (phospho Y153) antibody
    See all Caspase-9 primary antibodies
  • Description
    Rabbit polyclonal to Caspase-9 (phospho Y153)
  • SpecificityDetects Caspase-9 only when phosphorylated at tyrosine 153.
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-9.
    Database link: P55211

  • Positive control
    • ICC: HeLa cells; WB: extracts from COLO205 cells; IHC-P: thymus tissue.



Our Abpromise guarantee covers the use of ab79202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 46 kDa.
ELISA 1/10000.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.


  • FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
    Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
  • Tissue specificityUbiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
  • Sequence similaritiesBelongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Developmental stageExpressed at low levels in fetal heart, at moderate levels in neonate heart, and at high levels in adult heart.
  • Post-translational
    Cleavages at Asp-315 by granzyme B and at Asp-330 by caspase-3 generate the two active subunits. Caspase-8 and -10 can also be involved in these processing events.
  • Information by UniProt
  • Database links
  • Alternative names
    • APAF-3 antibody
    • APAF3 antibody
    • Apoptosis related cysteine peptidase antibody
    • Apoptotic protease Mch-6 antibody
    • Apoptotic protease-activating factor 3 antibody
    • CASP-9 antibody
    • CASP9 antibody
    • CASP9_HUMAN antibody
    • Caspase 9 apoptosis related cysteine peptidase antibody
    • Caspase 9 Dominant Negative antibody
    • Caspase 9c antibody
    • Caspase-9 antibody
    • Caspase-9 subunit p10 antibody
    • ICE LAP6 antibody
    • ICE like apoptotic protease 6 antibody
    • ICE-LAP6 antibody
    • ICE-like apoptotic protease 6 antibody
    • MCH6 antibody
    • PPP1R56 antibody
    • protein phosphatase 1, regulatory subunit 56 antibody
    • RNCASP9 antibody
    see all

Anti-Caspase-9 (phospho Y153) antibody images

  • Left panel: immunofluorescence analysis of HeLa cells using 1/500 ab89202. Right panel: same, after pre-incubation with the immunizing phosphopeptide.
  • Left panel: immunohistochemistry analysis of paraffin-embedded Human thymus tissue using 1/50 ab79202. Right panel: same, after pre-incubation with the immunizing phosphopeptide.
  • All lanes : Anti-Caspase-9 (phospho Y153) antibody (ab79202) at 1/500 dilution

    Lane 1 : COLO205 cell extracts
    Lane 2 : COLO205 cell extracts with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 46 kDa
    Observed band size : 46 kDa
    Additional bands at : 40 kDa (possible cleavage fragment).

References for Anti-Caspase-9 (phospho Y153) antibody (ab79202)

ab79202 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

Unfortunately, we do not currently know of any published references where anti-Caspase 9 (phospho Y153) antibody (ab79202) has been used. However, the antibody has been used in house to stain HeLa cells as well as...

Read More