Caspase Family Colorimetric Substrate Kit Plus (ab102486)

Overview

  • Product nameCaspase Family Colorimetric Substrate Kit Plus
    See all Caspase Family kits
  • Tests
    7 x 25 assay
  • Sample type
    Adherent cells, Suspension cells
  • Assay typeEnzyme activity
  • Species reactivity
    Reacts with: Human
  • Product overview

    Abcam's Caspase Family Colorimetric Substrate Kit Plus provides ready-to-use colorimetric substrates for members of caspase family proteases. All substrates are provided in liquid ready-to-use form.

    This kit is the idea tool to test which caspases are activated when apoptosis is induced in a particular cell type.
    Visit our FAQs page for tips and troubleshooting.

  • Tested applicationsSuitable for: Functional Studiesmore details

Properties

  • RelevanceCaspases are members of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
  • Cellular localizationCytoplasmic
  • Alternative names
    • CASP
    • CASP 2
    • CASP1
    • CASP2
    • Caspase
    • Caspase 1
    • Caspase 1 apoptosis related cysteine peptidase
    • Caspase 2
    • Caspase 2 apoptosis related cysteine peptidase
    • ICE
    • ICH 1 protease
    • ICH 1L
    • ICH 1L/1S
    • ICH1
    • IL 1 beta converting enzyme
    • IL1BC
    • Interleukin 1 B converting enzyme
    • Interleukin 1 beta convertase
    • Interleukin 1 beta converting enzyme
    • NEDD 2
    • NEDD2
    • NEDD2 apoptosis regulatory
    • Neural precursor cell expressed developmentally down regulated 2
    • Neural precursor cell expressed developmentally down regulated protein 2
    • P45
    • Protease ICH 1
    see all
  • Database links

Applications

Our Abpromise guarantee covers the use of ab102486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent dilution.

Protocols

References for Caspase Family Colorimetric Substrate Kit Plus (ab102486)

ab102486 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for contacting us with your questions.

We do have some panels for caspase activity measurement:

1) Ab102486: Includes substrates for caspases 1,2,3,5,6,8, and 9. It does not include substrates for caspases 4 and ...

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Gracias por tu paciencia.

Me han confirmado mis compañeros que este kit es compatible con cualquier muestra procedente de mamífero, incluyendo muestras de ratón.

El kit contiene diferentes sustratos con distinta...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"